Cutaneous T-Cell Lymphoma (Mycosis Fungoides)
نویسندگان
چکیده
منابع مشابه
Mycosis fungoides: cutaneous T-cell lymphoma.
Most patients with mycosis fungoides are between 40 and 60 years of age. The disease has three clinical stages: (1) the premycotic, or patch, stage, consisting of macular, scaling, faint pink to red pruritic patches, usually on unexposed surfaces; (2) the mycotic, or plaque, stage, consisting of reddish, purple-brown plaques, often annular in shape and symmetric in distribution, and (3) the tum...
متن کاملCutaneous T-Cell Lymphoma (Mycosis Fungoides).
IT IS IMPORTANT YOU DO NOT ACCEPT THE DIRE PROGNOSIS given in older medical literature you may find in a public library. Patients diagnosed and treated at early stages of CTCL can usually expect to live a NORMAL LIFESPAN and die of unrelated causes. For others, however, relapses are common, and treatment must either be lifelong in order to control the disease, or it must be repeated each time a...
متن کاملmiR-223 regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma
The pathogenesis of the cutaneous T-cell lymphoma (CTCL), mycosis fungoides (MF), is unclear. MicroRNA (miRNA) are small noncoding RNAs that target mRNA leading to reduced mRNA translation. Recently, specific miRNA were shown to be altered in CTCL. We detected significantly reduced expression of miR-223 in early-stage MF skin, and further decreased levels of miR-223 in advanced-stage disease. C...
متن کاملCoexpression of CD40 and CD40 ligand in cutaneous T-cell lymphoma (mycosis fungoides).
Microarray analysis is a promising new approach for creating specific expression profiles of multiple genes simultaneously. We quantitatively analyzed differential gene expression patterns in mycosis fungoides-derived clonal T cells and autologous, identically cultured CD4+ lymphocytes using microarrays containing 588 cDNA segments from genes relevant to cell signaling, carcinogenesis, and apop...
متن کاملNew insights into associated co-morbidities in patients with cutaneous T-cell lymphoma (mycosis fungoides).
Studies of associated cancer in patients with mycosis fungoides (MF) have focused primarily on secondary cancers in North American and European populations. This study investigated the association between MF and malignancies, anxiety and depression in the Israeli population. Data on Israeli patients with MF and age- and gender-matched controls were collected from a database of population- based...
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ژورنال
عنوان ژورنال: Medical Journal Armed Forces India
سال: 2007
ISSN: 0377-1237
DOI: 10.1016/s0377-1237(07)80076-1